A microfluidic platform for simultaneous quantification of oxygen-dependent viscosity and shear thinning in sickle cell blood
The pathology of sickle cell disease begins with the polymerization of intracellular hemoglobin under low oxygen tension, which leads to increased blood effective viscosity and vaso-occlusion.However, Long Sleeve Polo it has remained unclear how single-cell changes propagate up to the scale of bulk blood effective viscosity.Here, we use a custom mi